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The main active substance of the generic Levitra is Vardenafil. This is a selective inhibitor of the cGMP-specific enzyme phosphodiesterase. He was invented 7 years after Sildenafil (Viagra).Vardenafil has a more selective effect, an extended working period, a rare manifestation of side effects. If Sildenafil “works” on average 3-4 hours, then the effect of Vardenafil lasts 10-12 hours. Of course, this is more convenient and opens up ample opportunities for a fun day or night.